Senior Mechanical Design Engineer

Redwood City, California, United States Full-time

We are looking for a Senior Mechanical Design Engineer to join our team and help create the world’s first fully automated cloud-enabled molecular biology lab.

This position will own numerous projects, help build the tools to enable industrial-scale molecular biology research, and bring automation to genome engineering.



  • Mechanical design of scientific instruments in an industrial automation context


  • 5+ years of experience in mechanical design
  • 2+ year of experience in the automation space or instrument design or systems engineering
  • You have designed, built, tested and deployed complex automated instruments
  • You have had a very high level of ownership of the projects you worked on
  • You have designed and built in an industrial context where reliability matters
  • You have an extensive portfolio of badass projects to show us
  • You have a knack for cross-disciplinary problem-solving
  • You are a fast-paced self-starter who contributes innovative ideas
  • You love to work in a fast-paced, innovative and collaborative environment
  • You have good communication skills and a constructive, team dynamic, mindset
  • You are skilled at methodical self-management and project-management
  • You have a great sense of humor :-)
  • BS/MS in Mechanical Engineering and related work experience


  • SolidWorks, SolidWorks, SolidWorks
  • The design of custom motion solution, automated doors, clamps, pick and place gantries, belt drives, lead screw drives, bearing selection, seals, pneumatics, applied material science (chemical compatibility), temperature control, liquid handling
  • Familiarity with pneumatics
  • Familiarity with applied material science (chemical compatibility)
  • Seals

Bonus Qualifications

  • Generating wiring diagrams as well as P&ID (SolidWorks Electrical)
  • Strong Python programming skills are a major plus!
  • Quick turn / rapid prototyping experience
  • Previous experience in Biotech
  • Familiarity with microfluidics, pneumatic systems and reagent handling
  • ECAD - Altium Design, KiCAD
  • CAM - HSMWorks
  • CNC - Haas & Datron


Company Perks & Benefits

  • Competitive salary
  • Generous equity at an early stage company
  • Robust medical, dental and vision benefits
  • 401k Plan
  • Fully stocked kitchen and snacks
  • Free catered lunches and dinners
  • Onsite Machine Shop



Synthego is turning molecular biology into an information science. We're building hardware facilities that abstract biological syntheses and research into software.

Our vision is to bring automation to genome engineering, enabling scientists to run their own fully-automated laboratory at low cost, performing millions of controlled, repeatable experiments per day without human error.

Founded by former SpaceX engineers, Synthego is a leading provider of genome engineering solutions.  The company’s flagship product, CRISPRevolution, is a portfolio of synthetic RNA designed for CRISPR genome editing and research.

We are venture backed by Founders Fund, Menlo Ventures, 8VC, and WI Harper. 


Rev 20170119

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